Circadian Clocks Publications

  1. Welkie, D. G., Rubin, B. E., Chang, Y. -G., Diamond, S., Rifkin, S. A., LiWang, A., Golden, S. S. (2018) Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA, PNAS, in press.
  2. Swan, J. A., Golden, S. S., LiWang, A., Partch, C. L. (2018) Structure, function, and mechanism of the core circadian clock in cyanobacteria, J. Biol. Chem., 293, 5026-5034.
  3. Tseng, R.#, Goularte, N. F.#, Chavan, A.#, Luu, J., Cohen, S. E., Chang, Y.-G., Heisler, J., Li, S., Michael, A. K., Tripathi, S., Golden, S. S., LiWang, A.*, Partch, C. L.* (2017) Structural basis of the day-night transition in a bacterial circadian clock, Science, 355, 1174-1180. (* indicates corresponding author# indicates first author) [Highlighted in Nature Rev. Microbiol.]
  4. Chang, Y. -G., Cohen, S. E., Phong, C., Myers, W. K., Kim, Y., -I., Tseng, R., Lin, J., Zhang, L., Boyd, J. S., Lee, Y., Kang, S., Lee, D., Li, S., Britt, R. D., Rust, M., J., Golden, S., S., LiWang, A. (2015) A protein fold switch joins the circadian oscillator to clock output in cyanobacteria, Science, 349, 324-328. [Highlighted in Current Biology.]
  5. Roger, T., Chang, Y. -G., Bravo, I., Latham, R., Chaudhary, A., Kuo, N. -W., LiWang, A. (2014) Cooperative KaiA-KaiB-KaiC interactions affect KaiB/SasA competition in the circadian clock of cyanobacteria, J. Mol. Biol., 426, 389-402.
  6. Chang, Y. -G., Tseng, R., Kuo, N. -W., LiWang, A. (2013) Nuclear magnetic resonance spectroscopy of the circadian clock of cyanobacteria, Integ. Comp. Biol., 53, 93-102.
  7. Chang, Y. -G., Tseng, R., Kuo, N. -W., LiWang, A. (2012) Rhythmic ring-ring stacking drives the circadian oscillator clockwise, Proc. Natl. Acad. Sci. USA 109, 16847-16851. [Highlighted in C&ENPNAS, Nature Rev. Microbiol.]
  8. Chang, Y. -G., Kuo, N. -W., Tseng, R., LiWang, A. (2011) Flexibility of the C-terminal, or CII, ring of KaiC governs the rhythm of the circadian clock of cyanobacteria, Proc. Natl. Acad. Sci. USA 108, 14431-14436. [Highlighted in PNAS.]
  9. Wood, T. L., Bridwell-Rabb, J., Gao, T., Chang, Y. -G., Kim, Y. -I., LiWang, A., Barondeau, D. P., Golden, S. S. (2010) The KaiA protein of the cyanobacterial circadian oscillator is modulated by a redox-active cofactor, Proc. Natl. Acad. Sci, USA 107, 5804-5809.
  10. Chen, Y., Kim, Y. -I., Mackey, S. R., Holtman, C. K., LiWang, A., Golden, S. S. (2009) A novel allele of kaiA shortens period and strengthens interaction of oscillator components in the cyanobacterium Synechococcus elongatus PCC 7942 J.Bacteriol. 191, 4392-4400.
  11. Vakonakis, I., LiWang, A. (2009) NMR Studies of a Timekeeping System in Bacterial Circadian Programs, Eds. Ditty, J. L., Mackey, S. R., Springer, Heidelberg.
  12. Kim, Y. -I., Dong, G., Carruthers, C., Golden, S. S., LiWang, A. (2008) The day/night switch in KaiC, a central oscillator component of the circadian clock of cyanobacteria, Proc. Natl. Acad. Sci. USA. 105, 12825-12830.
  13. Golden, S. S., Cassone, V. M., LiWang, A. (2007) News & Views: shifting nanoscopic clock gears, Nat. Struct. Mol. Biol. 14, 362-363.
  14. Gao, T., Zhang, X., Golden, S. S., LiWang, A. (2007) NMR structure of the pseudo-receiver domain of CikA, Protein Sci. 16, 465–475.
  15. Ivleva, N. B., Gao, T., LiWang, A., Golden, S. S. (2006) Quinone sensing by the circadian input kinase of the cyanobacterial circadian clock Proc. Natl. Acad. Sci. USA 103, 17468–17473. [Highlighted in F1000.]
  16. Gao, T., Zhang, X., Xia, Y., Cho, Y., Sacchettini, J. C., Golden, S. S., LiWang, A. (2005) 1H, 13C and 15N chemical shift assignments of the C-terminal, 133-residue pseudo-receiver domain of circadian input kinase (CikA) in Synechococcus elongatus, J. Biomol. NMR 32, 259.
  17. Vakonakis, I., Klewer, D. A., Williams, S. B., Golden, S. S., LiWang, A. (2004) Structure of the N-terminal sensory domain of the circadian clock associated histidine kinase SasA, J. Mol. Biol. 342, 9–17.
  18. Vakonakis, I., LiWang, A. (2004) Structure of the C-terminal domain of the clock protein KaiA in complex with a KaiC-derived peptide: implications for KaiC regulation, Proc. Natl. Acad. Sci. USA 101, 10925–10930. [Highlighted in C&EN.]
  19. Ye, S.#, Vakonakis, I.#, Ioerger, T. R., LiWang, A.* Sacchettini, J. C.* (2004) Crystal structure of circadian clock protein KaiA from Synechococcus elongatus, J. Biol. Chem. 279, 20511–20518. (* indicates corresponding author; # indicates first author)
  20. Vakonakis, I., Sun, J., Wu, T., Holzenburg, A., Golden, S. S., LiWang, A. (2004) NMR structure of the KaiC-interacting C-terminal domain of KaiA, a circadian clock protein:  implications for the KaiA–KaiC interaction, Proc. Natl. Acad. Sci. USA 101, 1479–1484.[Highlighted in F1000.]
  21. Vakonakis, I., LiWang, A. (2004) Sequence-specific 1H, 13C and 15N resonance assignments of the C-terminal domain of KaiA, a circadian clock protein, J. Biomol. NMR 28, 403–404.
  22. Williams, S. B., Vakonakis, I., Golden, S. S., LiWang, A. (2002) Structure and function of the circadian clock protein KaiA of Synechococcus elongatus: a potential clock input mechanism, Proc. Natl. Acad. Sci. U.S.A. 99, 15357-15362.
  23. Klewer, D. A., Williams, S. B., Golden, S. S., LiWang, A. (2002) Sequence-specific resonance assignments of the N-terminal, 105-residue KaiC-interacting domain of SasA, a protein necessary for a robust circadian rhythm in Synechococcus elongatus, J. Biomol. NMR 24, 77-78.
  24. Vakonakis, I., Risinger, A. T., Latham, M. P., Williams, S. B., Golden, S. S., LiWang, A. (2001) Sequence-specific 1H, 13C, 15N resonance assignments of the N-terminal, 135-residue domain of KaiA, a clock protein from Synechococcus elongatus, J. Biomol. NMR 21, 179–180.